Anish Mukherjee, PhD
Anish completed his undergraduate degree in Electrical Engineering from Jadavpur University in India. He went on to complete his PhD in BioEngineering from Georgia Tech, in the lab of Dr. J. Brandon Dixon. During his PhD, Anish investigated the role of the oscillatory mechanical microenvironment of lymphatics on their contractile function, with the ultimate goal of finding therapeutic strategies for reducing lymphedema by targeting the collecting lymphatics. He is currently a postdoctoral scholar in the lab of Dr. Melody Swartz.
Anish is looking to delineate the multifaceted role of lymphatic vessels in cancer. He is specifically looking at how cancer therapies, such as radiotherapy, can affect the structure and function of the local lymphatic vasculature and what it entails for cancer therapy and metastasis.
Effect of Human Synovial Fluid From Osteoarthritis Patients and Healthy Individuals on Lymphatic Contractile Activity.
Michalaki E, Nepiyushchikh Z, Rudd JM, Bernard FC, Mukherjee A, McKinney JM, Doan TN, Willett NJ, Dixon JB.J Biomech Eng. 2022 Jul 1;144(7):071012. doi: 10.1115/1.4053749.
Lymphatic injury alters the contractility and mechanosensitivity of collecting lymphatics to intermittent pneumatic compression. Mukherjee A, Nepiyushchikh Z, Michalaki E, Dixon JB.J Physiol. 2021 Feb 28. doi: 10.1113/JP281206.
Entrainment of Lymphatic Contraction to Oscillatory Flow.
Mukherjee A, Hooks J, Nepiyushchikh Z, Dixon JB.Sci Rep. 2019 Apr 9;9(1):5840. doi: 10.1038/s41598-019-42142-9.PMID: 30967585
Mechanotransduction activates canonical Wnt/β-catenin signaling to promote lymphatic vascular patterning and the development of lymphatic and lymphovenous valves.
Cha B, Geng X, Mahamud MR, Fu J, Mukherjee A, Kim Y, Jho EH, Kim TH, Kahn ML, Xia L, Dixon JB, Chen H, Srinivasan RS.Genes Dev. 2016 Jun 15;30(12):1454-69. doi: 10.1101/gad.282400.116. Epub 2016 Jun 16.PMID: 27313318
Effects of dynamic shear and transmural pressure on wall shear stress sensitivity in collecting lymphatic vessels.
Kornuta JA, Nepiyushchikh Z, Gasheva OY, Mukherjee A, Zawieja DC, Dixon JB.Am J Physiol Regul Integr Comp Physiol. 2015 Nov 1;309(9):R1122-34.